Refereed Journal Papers
2016
Link | Khosravi R, Best CA, Allen RA, Stowell CET, Onwuka E, Zhuang JJ, Lee YU, Yi T, Bersi MR, Shinoka T, Humphrey JD, Wang Y, Breuer CK. Long-term functional efficacy of a novel electrospun poly(glycerol sebacate)-based arterial graft in mice. Annals of Biomedical Engineering. In Press. | |
Link | Hassan K. Awada, Mintai P. Hwang, Yadong Wang. Towards comprehensive cardiac repair and regeneration after myocardial infarction: Aspects to consider and proteins to deliver. Biomaterials. 82: 94-112, 2016. |
2015
Link | Chen C-W, Lee B, Park D, Kim K, Chu H, Kim K, Huard J, and Wang Y. Controlled Dual Delivery of Fibroblast Growth Factor-2 and Interleukin-10 by Heparin-based Coacervate Synergistically Enhances Ischemic Heart Repair. Biomaterials. 72: 138–151, 2015. | |
Link | Johnson NR, Kruger M, Goetsch K, Zilla P, Bezuidenhout D, Wang Y, Davies N. "Coacervate delivery of growth factors combined with a degradable hydrogel preserves heart function after myocardial infarction". ACS Biomater Sci Eng. 1(9): 753–759, 2015. |
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Link | Sinha M, Stowell C, Gao J, and Wang Y Synthesis and Biocompatibility of a Biodegradable and Functionalizable Thermo-Sensitive Hydrogel. Regenerative Biomaterials. 177-185, 2015. |
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Link | Johnson NR, Wang Y. Coacervate delivery of HB-EGF accelerates healing of type 2 diabetic wounds. Wound Repair Regen. 66:67-82, 2015. |
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Link | Xie Q, Wang Z, Huang Y1, Bi X, Zhou H, Lin M, Yu Z, Wang Y, Ni N, Sun J, Wu S, You Z, Guo C, Sun H, Wang Y, Gu P, and Fan X. Characterization of human ethmoid sinus mucosa derived mesenchymal stem cells (hESMSCs) and the application of hESMSCs cell sheets in bone regeneration. Biomaterials 66:67-82, 2015. |
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Link | Awada H, Johnson N and Wang Y. Sequential delivery of angiogenic growth factors improves revascularization and heart function after myocardial infarction. J. Control. Release. 207:7-17, 2015. |
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Link | Jeffries E, Allen R, Gao J, Pesce M, and Wang Y. Highly Elastic and Suturable Electrospun Poly(Glycerol Sebacate) Fibrous Scaffolds.Acta Biomater. , 18:30-39, 2015. |
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Link | Johnson NR, Wang Y. Drug delivery systems for wound healing. Curr Pharm Biotech. 16(7): 621-9, 2015. |
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Link | Rauck B, Novosat T, Oudega M, and Wang Y. Biocompatibility of a Coacervate-Based Controlled Release System for Protein Delivery to the Injured Spinal Cord. Acta Biomater. In press. |
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Link | Robertson F, Wang Y, Rosing H. An oligomeric switch that rapidly decreases the peel strength of a pressure sensitive adhesive. Int. J. Adhes. Adhes. 55: 64-8, 2014. |
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Link | Johnson NR, Wang Y. “Controlled Delivery of Sonic Hedgehog with a Heparin-Based Coacervate”. Hedgehog Signaling Protocols, 2nd ed. Methods in Molecular Biology. 1322:1-7. |
2014
Awada H, Johnson N and Wang Y. Sequential delivery of angiogenic growth factors improves revascularization and heart function after myocardial infarction. J. Control. Release. In Press |
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Link | Allen RA, Wu W, Yao M, Dutta D, Duan X, Bachman TN, Champion HC, Stolz DB, Robertson AM, Kim K, Isenberg JS, and Wang Y. Nerve regeneration and elastin formation within poly(glycerol sebacate)-based synthetic arterial grafts one-year post-implantation in a rat model. Biomaterials. , 35(1):165-73, 2014. |
Link | Ritfeld GJ, Rauck B, Novosat TL, Park D, Patel P, Roos RAC, Wang Y*, and Oudega M*. The effect of a polyurethane-based reverse thermal gel on bone marrow stromal cell transplant survival and spinal cord repair. Biomaterials. , 35(6): 1924-1931, 2014. |
Link | Deng Y, Bi X, Zhou H, You Z, Wang Y, Gu P, Fan X. Repair of critical-sized bone defects with anti-miR-31-expressing bone marrow stromal stem cells and poly (glycerol sebacate) scaffolds. European Cells and Materials. , 27, 13-25, 2014. |
Link | Rauck BM, Friberg TR, Mendez CAM, Park D, Shah V, Bilonick RA, and Wang Y. Biocompatible reverse thermal gel sustains the release of intravitreal bevacizumab in vivo. Invest. Ophthalmol. Vis. Sci. , 55: 469-476, 2014. |
Link | Zaky S, Tudares M, Alejandro, Almarza A, Hagandora C, Jensen AD , Gao J, Wang Y, Sfeir C. Poly (glycerol sebacate) elastomer supports osteogenic phenotype for bone engineering applications. Biomed. Mater. , 9, 025003, 2014. |
Link | Bi X, You Z, Gao J, Fan X, Wang Y.A functional polyester carrying free hydroxyl groups promotes the mineralization of osteoblast and human mesenchymal stem cell extracellular matrix. Acta Biomater. , 10(6):2814-23, 2014. |
Link | Rauck BM, Novosat TL, Oudega M, Wang Y. Biocompatibility of a coacervate-based controlled release system for protein delivery to the injured spinal cord. Acta Biomaterialia In Press |
Link | Jeffries E, Nakamura S, Lee K-W, Clampffer J, Ijima H, and Wang Y. Micropatterning Electrospun Scaffolds to Create Intrinsic Vascular Networks. Macromol. Biosci. 14(11): 1514–1520, 2014. Featured in “Best of Macromolecular Journals-Edition 2015”. |
Link | Johnson NR, Wang Y. Coacervate delivery systems for proteins and small molecule drugs. Expert Opin Drug Del 11(12):1829-1832 |
Link | Johnson NR, Ambe T, Wang Y. Lysine-based polycation:heparin coacervate for controllable sustained release. Acta Biomaterialia, 10(1):40-46. |
Link | Awada HK, Johnson NR, Wang Y. Dual Delivery of Vascular Endothelial Growth Factor and Hepatocyte Growth Factor Coacervate Displays Strong Angiogenic Effects. Macromol Biosci, 14(5):679-686. |
2013
Link | Rauck BM, Friberg TR, Mendez CAM, Park D, Shah V, Bilonick RA, and Wang Y. Biocompatible reverse thermal gel sustains the release of intravitreal bevacizumab in vivo. Invest. Ophthalmol. Vis. Sci, In Press |
Link | Allen RA, Wu W, Yao M, Dutta D, Duan X, Bachman TN, Champion HC, Stolz DB, Robertson AM, Kim K, Isenberg JS, Wang Y. Nerve regeneration and elastin formation within poly(glycerol sebacate)-based synthetic arterial grafts one-year post-implantation in a rat model. Biomaterials, 35:167-73. |
Link | Yu J, Takanari K, Hong Y, Lee KW, Amoroso N, Wang Y, Wagner W, Kim K. Non-invasive Characterization of Polyurethan-based Tissue Constructs on Rat Abdominal Repair Model Using High Frequency Ultrasound Elasticity Imaging. Biomaterials, 34(11):2701-2709. |
Link | Dutta D, Lee KW, Allen RA, Wang Y, Brigham JC, Kim K. Non-invasive Assessment of Elastic Modulus in Arterial Constructs During Cell Culture using Ultrasound Elasticity Imaging. Ultrasound in Med & Biol, 39(11):2103-2115. |
Link | Lee KW, Johnson NR, Gao J, Wang Y.Human Progenitor Cell Recruitment via SDF-1 alpha Coacervate-laden PGS Vascular Grafts. Biomaterials, 34(38):9877-9885. |
Link | Zaky SH, Lee KW, Gao J, Jensen A, Wang Y, Almarza AJ, Sfeir C. Poly(glycerol sebacate) Elastomer, a Novel Material for Mechanically Loaded Bone Regeneration. Tissue Eng Part A. , In press. |
Link | Jeffries EM, Wang Y. Incorporation of parallel electrospun fibers for improved topographical guidance in 3D nerve guides. Biofabrication, 5(3). |
Link | Johnson NR, Li H, Usas A, Lu A, Wang Y, Huard J. Sustained Release of BMP2 via Coacervate Improves the Osteogenic Potential of Muscle-Derived Stem Cells. Stem Cells Transl Med, 2(9):667-77. |
Link | Johnson NR and Wang Y. Controlled delivery of Sonic hedgehog morphogen and its potential for cardiac repair. PLoS One, 8(5): e63075. |
Link | Park D, Shah V, Rauck B, Friberg TR, and Wang Y. An anti-angiogenic reverse thermal gel as a drug delivery system for age-related wet macular degeneration. Macromol. Biosci, In Press. |
Link | Chu H, Chen C-W, Huard J, and Wang Y. The effect of a heparin-based coacervate of fibroblast growth factor-2 on scarring in the infarcted myocardium. Biomaterials, 34(6):1747-56. |
Link | Johnson N and Wang Y. Controlled delivery of heparin-binding EGF-like growth factor yields fast and comprehensive wound healing. J. Control. Release, 166(2):124-9. |
Link | Park D, Larson AM, Klibanov AM, Wang Y. Antiviral and antibacterial polyurethanes of various modalities. App. Biochem. Biotechnol., 169(4): 1134-1146. |
Link | Hagandora K, Gao J, Wang Y, Almarza AJ. Poly (glycerol sebacate): a novel scaffold material for temporomandibular joint disc engineering. Tissue Eng., 19(5-6): 729-737. |
2012
Link | Bae H, Chu H, Edalat F, Cha JM, Sant S, Kashyap A, Ahari AF, Kwon CH, Nichol JW, Manoucheri S, Zamanian B, Wang Y, and Khademhosseini A. Development of functional biomaterials with micro- and nanoscale technologies for tissue engineering and drug delivery applications. J Tissue Eng Regen Med. , 6: 1-14. |
Link | Chu H, and Wang Y. Therapeutic Angiogenesis: Controlled Delivery of Angiogenic Factors. Therapeutic Delivery, 3: 693-714. |
Link | You Z, Wang Y. A Versatile Synthetic Platform for a Wide Range of Functionalized Biomaterials. Advanced Functional Materials, 22: 2812-20. |
Link | Wu W, Allen R, and Wang Y. Fast Degrading Elastomer Enables Rapid Remodeling of a Cell-Free Synthetic Graft into a Neo-Artery. Nature Medicine, 18: 1148-1153. |
Link | Jeffries EM and Wang Y. Biomimetic Micropatterned Multi-channel Nerve Guides by Templated Electrospinning. Biotechnology and Bioengineering, 109: 1571-82. |
Link | You Z, Bi X, and Wang Y. Fine Control of Polyester Properties via Epoxide-opening Polymerization Using Monomers Carrying Diverse Functional Groups. Macromolecular Bioscience, 12: 822-9. |
Link | Chu H, Gao J, and Wang Y. Design, synthesis, and biocompatibility of an arginine-based polyester. Biotechnology Progress., 28: 257-264 |
Link | You Z, Bi X, Fan X, and Wang Y. A functional polymer designed for bone tissue engineering. Acta Biomaterialia., 8: 502-510 |
Link | You Z, Bi X, Jeffries EM, and Wang Y. A biocompatible, metal-free catalyst and its application in microwave-assisted synthesis of functional polyesters. Polymer Chemistry, 3:384-389. |
2011
Link | Allen, R and Wang Y. Rapid Self-Assembly of Tubular Arterial Media Layer from Smooth Muscle Cells in Transient Fibrin Gel.J Tissue Sci Eng. 2:105e. |
Link | Chu H, Gao J, Chena C, Huard J, and Wang Y. Injectable fibroblast growth factor-2 coacervate for persistent angiogenesis. PNAS. |
Link | Zern BJ, Chu H, Osunkoya AO, Gao J, and Wang Y. A Biocompatible Arginine-based Polycation. Adv. Func. Mater., 21: 434-440 |
Link | Chu H, Johnson NR, Mason NS, and Wang Y. A [polycation:heparin] complex releases growth factors with enhanced bioactivity. J. Control. Release, 150, 157-163 |
Link | Park D, Wu W, and Wang Y. A functionalizable reverse thermal gel based on a polyurethane / PEG block copolymer. Biomaterials, 32:777-786 |
Link | Crapo P and Wang Y. Hydrostatic Pressure Independently Increases Elastin and Collagen Co-expression in Small-diameter Engineered Arterial Constructs. J. Biomed. Mat. Res., 96(4):673-81 |
Link | Lee K-W, Stolz DB, and Wang Y. Substantial Expression of Mature Elastin in Arterial Constructs. Proc. Natl. Acad. Sci. U.S.A., 108:2705-10 |
Link | Wu W, Allen R, Gao J, and Wang Y Artificial Niche Combining Elastomeric Substrate and Platelet Guided Vascular tissue formation of Bone Marrow Mononuclear Cells. Tissue Eng |
Link | Gumera C, Rauck B, and Wang Y. Materials for Central Nervous System Regeneration: Bioactive Cues. J. Mater. Chem., 21, 7033 - 7051 |
Link | Lee K-W and Wang Y: Elastomeric PGS Scaffolds in Arterial Tissue Engineering. http://www.jove.com/details.stp?id=2691 doi: 10.3791/2691. J. Vis. Exp. 50 |
Link | Wilson ME, Kota N, Kim YT, Wang Y, Stolz DB, LeDuc P, and Ozdoganlar BO. Fabrication of Circular Microfluidic Channels by Combining Mechanical Micromilling and Soft Lithography. Lab Chip. 11, 1550-1555 |
2010
Link | Crapo PM and Wang Y. Small Intestinal Submucosa Gel as a Potential Scaffolding Material for Cardiac Tissue Engineering. Acta Biomater., 2091-2096 |
Link | Crapo PM and Wang Y. Physiologic Compliance In Engineered Small-Diameter Arterial Constructs Based On An Elastomeric Substrate. Biomaterials, 31: 1626-1635 |
Link | You Z, Cao H, Gao J, Shin, PH, Day BW, and Wang Y. A functionalizable polyester with free hydroxyl groups and tunable physiochemical and biological properties. Biomaterials, 31: 3129-3138 |
Link | Zern BJ, Chu H, and Wang Y. Control growth factor release using a self-assembled [polycation:heparin] complex. PLoS ONE, 5, e11017. doi:10.1371 |
Link | Marsano A, Maidhof R, Wan LQ, Wang Y, Gao J, Tandon N, and Vunjak-Novakovic G. Scaffold stiffness affects the contractile function of three dimensional engineered cardiac constructs, Biotechnol. Prog., 26: 1382-1390 |
2009
Link | Secasanu V, Giardina C, and Wang Y. A novel electrospinning target for improved yield of uniaxially aligned fibers. Biotechnol. Prog. 25: 1169-1175 |
Link | Lee EJ, Vunjak-Novakovic G, Wang Y, and Niklason LE. A biocompatible endothelial cell delivery system for in vitro tissue engineering. Cell Transplant. 18: 731-743 |
2008
Link | Gao J, Crapo PM, Nerem R, and Wang Y. Co-Expression of Elastin and Collagen Leads to Highly Compliant Engineered Blood Vessels. J. Biomed. Mat. Res. 85A: 1120-1128 |
Link | Crapo PM, Gao J, and Wang Y. Seamless Tubular Poly(glycerol sebacate) Scaffolds: High-yield Fabrication and Potential Applications. J. Biomed. Mat. Res. 86: 354-363 |
Link | Radisic M, Park H, Salazar-Lazaro JE, Wang Y, Langer R, Freed LE, and Vunjak-Novakovic G. Pretreatment of Synthetic Elastomer Scaffolds by Cardiac Fibroblasts Improves Engineered Heart Tissue. J. Biomed. Mat. Res. 86: 713-724 |
Link | Radisic M, Marsano A, Maidhof R, Wang Y, and Vunjak-Novakovic G. Cardiac tissue engineering using perfusion bioreactor systems. Nat. Protoc. 3: 719-738 |
2007
Link | Gumera C and Wang Y. Modulating neuronal responses by controlled integration of acetylcholine-like functionalities in biomimetic polymers. Adv. Mater. 19: 4404-4409 |
Link | Gao J, Ensley A, Nerem R, and Wang Y. Poly (glycerol sebacate) Supports the Proliferation and Phenotypic Protein Expression of Primary Baboon Vascular Cells. J. Biomed. Mat. Res. 83: 1070-1075 |
Link | Kim YM, Gao J, Zern B, and Wang Y. Biofunctional materials for Nerve Regeneration. Mater. Sci. Forum, 539: 547-550 |
Link | Sales VL, Engelmayr GC, Gottlieb D, Johnson JA, Gao J, Wang Y, Sacks MS, and Mayer JE. Protein Precoating of Elastomeric Tissue-Engineering Scaffolds: Extracellular Matrix Formation and Phenotypic Changes of Circulating Endothelial Progenitor Cells. Circ. Res., 99: e35 |
2006
Link | Gao J, Crapo PM, and Wang Y. Macroporous Elastomeric Scaffolds with Extensive Micropores for Soft Tissue Engineering. Tissue Eng., 12: 917-925 |
Link | Gao J, Kim YM, Coe H, Zern B, Sheppard B, and Wang Y. A Neuro-inductive Biodegradable Material Based on Dopamine. Proc. Natl. Acad. Sci. U.S.A., 103: 16681-16686 |
Link | Radisic M, Park H, Chen F, Wang Y, Dennis R, Langer R, Freed LE, and Vunjak-Novakovic G. Biomimetic Approach to Cardiac Tissue Engineering: Oxygen Carriers and Channeled Scaffolds. Tissue Eng., 12: 1-15 |
Link | Bettinger CJ, Weinberg E, Wang Y, Borenstein J, and Langer R. Three-dimensional Microfluidic Tissue Engineering Scaffolds Using a Flexible Biodegradable Polymer. Adv. Mater. 18: 165-169 |
2005
Link | Fidkowski C, Kaazempur-Mofrad MR, Borenstein J, Vacanti JP, Langer R, and Wang Y. Endothelialized Microvasculature Based on a Biodegradable Elastomer. Tissue Eng., 11: 302-309 |
Link | Haaga J, Exner A, Wang Y, Stowe N, and Tarcha PJ. Combined Tumor Therapy by Using Radiofrequency Ablation and 5-FU-Laden Polymer Implants: Evaluation in Rats and Rabbits. Radiology, 911-918 |
Link | Sundback CA, Shyu JY, Wang Y, Faquin WC, Langer R, Vacanti JP, and Hadlock TA. Biocompatibility Analysis of Poly(glycerol sebacate) as a Nerve Guide Material. Biomaterials, 26: 5454-5464 |
1996-2004
Link | Ijima H, Wang Y, and Langer R. Spheroid Formation and Expression of Liver Specific Functions of Primary Rat Hepatocytes Co-cultured with Bone Marrow Cells. Biochem. Eng. J., 20: 223-228 |
Link | Wang Y, Kim YM, and Langer R. In vivo Degradation characteristics of Poly(glycerol sebacate). J. Biomed. Mat. Res. 66A: 192-197 |
Link | Wang Y, Ameer GA, Sheppard BJ, and Langer R. A Tough Biodegradable Elastomer. Nat. Biotechnol., 20: 602-606 |
Link | Wang Y, DuBois JL. Hedman B, Hodgson KO, and Stack TDP Catalytic Galactose Oxidase Models: Biomimetic Cu(II)-Phenoxyl-Radical Reactivity. Science, 279: 537-540 |
Link | Wang Y and Stack, TDP. Galactose Oxidase Model Complexes: Catalytic Reactivities. J. Am. Chem. Soc., 118: 13097-13098 |